About 50 people attended the event, which raised £300 for Oxfam.
There were almost 20 group and solo performances by the pupils, who are all 17 and in the first year of their BTEC music diploma.
They played cover versions of pop and rock songs including Fix You and What If by Coldplay, I Predict A Riot by Kaiser Chiefs and Plug In Baby by Muse.
Guitarist Liam Tse played Ben Howard?s Under The Same Sun, which involves tapping rhythms on the body of an acoustic guitar.
Chris Mears performed two original compositions and Lissie Smith played her own song called Come Lay Next To Me. Somer Jassim, Liam Tse, Cameron Ferguson and Charlie Hutchinson played the final number, a song they wrote called Height.
Another group from the college?s 23 music students held a separate gig at the club in Deanfield Road and raised more than £200.
The students had to arrange the event as part of their course and raise enough money to cover their costs, which they achieved by busking in Oxford and holding cake sales. They designed and printed their own flyers and programmes and publicised the gig on Facebook and Twitter.
They had six weeks to put it all together and spent about three hours a week rehearsing.
Music lecturer Alison Golby said: ?The students rose to the challenge and raised a lot of money.?