MUMBERY HILL in Wargrave (the B477) will be closed between its junctions with the A4 Bath Road and Harvest Place from Monday until Monday, October 24.
The closure is to enable Wokingham Borough Council contractors to carry out essential maintenance.
The alternative route will be via the A4 Bath Road, A321 Wargrave Road, A321 High Street, B477 School Lane and B477 School Road.
The council says the closure will only be in effect while the necessary signs are displayed. Access for residents and businesses will be maintained at all times.